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It could be due to the Subconscious Limits Removal process. Perhaps try adding Emotional Release, Atmospheric Vibration Raiser and Depression/Stress/Anxiety Relief and see how you go. You can also listen to it less often until the depression and anxiety fade, if it seems to be too much at once.
This conversation with Sam from the Sapien team in the General Discussion thread may be relevant to what you describe:
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