8 posts were merged into an existing topic: Social General
Guys please this thread went completely out of topicā¦ there are many threads about that
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wheatgerm contains so many wonderful chemicals spermidine, Activator X ā¦
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I remember about autophagy reducing the amount of senescent cells, pain and then improving well being aswell. This process is key in antiaging.
Thanks for bring this up, I didnāt noticed it at all.
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So a little birdie suggested I listen to this oddly named field ā¦
Looking in the mirror several hours later, I swear I look 16 year old 
As always, your mileage may vary.
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Picture or it didnāt happen. 
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ahh i am sure if he says 16 year old, he is right.
Om is 147 so i am quite sure he knows the difference between 147 and 16.
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I even lie about my age to youā¦
Iām literally so beautiful now, Iād blind you permanently. Itās for the best to not see me.
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Donāt worry! I have excellent sunglasses. 
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I was just reading the post ahead and had this exact thread.
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This is definitely on my list and Iāll tell you why .
The increase in NAD+ acts on such a fundamental level that this is basically helpfull for everything!
From athleticism to looks and chronic diseases .
Here are some examples:
1.Increasing NAD may treat ALS (incurable) :
" ā¦To investigate this, we measured NAD+ levels in mitochondria isolated from iPSC-derived MNs and found 60ā80% reduction in NAD+ levels in the mitochondria of sporadic, familial, and isogenic ALS MNs when compared to healthy controls (Fig. 5a). To increase mitochondrial NAD+, 0.5 mM NAM was used, resulting in significantly elevated mitochondrial NAD+ in ALS MNs (Fig. 5a). We found that NAM treatment promoted ALS MN survival (Fig. 5b) and improved basal mitochondrial respiration, ATP production as well as spare respiratory capacity (Fig. 5d, e), reversing ALS phenotypes."
(https://pubmed.ncbi.nlm.nih.gov/33184465/)
2.NAD may treat glaucoma (incurable)
" āā¦An additional key difference in metabolic profiles between control and glaucoma retinas was a decrease in retinal NAM. NAM levels were lower in D2 retinas compared to controls consistent with decreased retinal nicotinamide adenine dinucleotide (NAD) levels in this model (7) and decreased serum NAM levels in primary open angle glaucoma patients (23). We have previously demonstrated that NAM confers a robust neuroprotection against damaging IOP insults. NAM supplementation prevents age-dependent decreases in NAD levels, transcriptional reprogramming of RGCs, mitochondrial decline, and RGC neurodegeneration (5, 7, 24, 25).
" In conclusion, these findings are consistent with a model of glaucoma where elevated IOP disrupts energy homeostasis by affecting the availability of metabolic energy substrates . Further affected by low availability of coenzymes, such as NAD+, RGCs ultimately lack the energy needed to function and cope with stress and inflammation associated with age and ocular hypertension. Energy supplementation not only reduces degeneration, but also improves visual function . In this light, decreased visual function prior to degeneration may be an adaptive response to reduce energy consumption and signal a need for energy supplements. Although the combination of decreased NAD and pyruvate represent a critical component of RGC susceptibility in glaucoma, it is directly therapeutically approachable"
(https://www.pnas.org/content/117/52/33619)
3.It may help / treat covid 19
ā¦A new preclinical study found that SARS-CoV-2 (the virus that causes COVID-19) infection of cell lines, infected ferrets, and a deceased patientās lung dysregulates nicotinamide adenine dinucleotide (NAD+) synthesis and utilization .
We started by looking at the effect of a related coronavirus that infects mice. It disturbs the gene set that controls cellular NAD . Moreover, we showed that within 12 hours of initial infection, the virus greatly depresses levels of NAD, the central catalyst of metabolism.ā
Our data says that the innate immune defense against viral infection depends on NAD and that it may be more effective at higher NAD,ā says Brenner.
4.NAD can reduce liver damage (from alcohol) and increases mitochondrial health:
āExcessive alcohol consumption and binge drinking reduce levels of free nicotinamide adenine dinucleotide (NAD+) critical to cellular health and energy production, resulting in liver and organ damage.ā
" Chronic alcohol use and binge drinking can add to these effects by reducing NAD+ levels and contributing to the dysfunction of sirtuins and, ultimately, mitochondria. The review suggests that increasing levels of NAD+ can elevate sirtuin activity to promote beneficial cellular effects, such as the generation of new mitochondria. Along these lines, research has shown that NAD+ boosters like nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) can prevent mitochondrial deterioration."
(https://www.nmn.com/news/binge-drinking-causes-liver-damage-by-reducing-bodily-levels-of-nad)
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Idk if itās this or from listening to the Ambrosia livestream yesterday and today for an hour or bothā¦but I DEF look younger and healthier than I did a few days ago.
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Alright
I bought this, a thorough and honest review coming in 2 weeks or less 
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How many times you listen to this bro?
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3x a day
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Oh okay, its given me too much energy at 11:30pm 
This will be in my morning stack
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dayum this has nice music. I am a escapist of some sorts especially when it comes to music. I could listen to this all day 
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Right bro!
Whereās number 1-30 
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