broooooooooooooooooooooooo
don’t delete comments
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Most interesting part of the article hmmm yes
Conflicts of Interest
The authors declare no conflicts of interest.
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Mitochondrial uncoupling is often perceived as an isolated cellular mechanism or a dysfunction. However, the induction of such a condition not only impacts mitochondrial respiration but can also activate or hamper multiple cellular mechanisms, including bulk and specific forms of autophagy, ROS production regulation, protein secretion, physical exercise capacity, and adipose tissue biology (Figure 1). These responses are complex and often rely on the combination of several biological features (species, cell type), physical (temperature), and/or chemical (ion concentration, lipid composition of membranes, nature of the uncoupler) parameters. Unfortunately, the cellular consequences have not been studied rigorously. Indeed, most mechanistic studies have focused on the impact of classical but non-specific mitochondrial uncouplers, such as DNP or FCCP. Therefore, it could be difficult to discriminate effects directly imputable to mitochondrial uncoupling from unspecific effects. The continuous development of new mitochondria-specific uncoupling agents should greatly improve our knowledge of the cellular consequences of mitochondrial uncoupling. Moreover, the identification of such compounds, safer than classic DNP, should also eliminate their use in the treatment of human diseases, such as obesity (and associated complications) or some forms of cancers, in order to improve safety.
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The more i read the more confusing it gets.
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well it says in a nutshell they are plenty of things the uncoupling does
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but they are complex things to study because they have limited things to experiement
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Anyone else have any question so I can research?
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it saddens me that people reading the thread and not participating so vote please here what should we do for you to participate.
- SaintTheophilos do clown dance
- SainBicep to do more bean jokes
- To do all together love graviton meditation in the thread
- To learn more stuff together
- To learn more stuff alone
- To not learn a thing
- To be more funny
- To be more edgy
- To have fake drama between Saint brothers
- To become a global force first and then you will come
- To become wise and tell wise things to each other
0 voters
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yes yes true yes
relatable
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I delete cuz u delete now idk what to do
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I undelete
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Oh shit u can see whos voted what.
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we know who you are now
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Done voted
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How to get to point B from point A with out skipping C?
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I voted too but ik it doesn’t even matter cuz the elections are rigged, i win every time smh
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you start from A then proceed to C then B
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you just a fried potato now bro
smh smh smh
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