The Cholesterol Vaccine

This works on PCSK9, it downregulates and removes it from your body.
PCSK9 is a protein produced in the body, that instructs the body to produce LDL and to raise LDL levels. Without this protein / instruction. The LDL levels diminish and there is a higher ratio of HDL.

Use as needed

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Switch the section to new releases so others get notifcations :slightly_smiling_face:

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Low-Density Lipoprotein (LDL) plays a crucial role in the body’s metabolism, particularly in the transport and management of lipids (fats). Here are its primary functions:

  1. Transport of Cholesterol: LDL is often referred to as “bad cholesterol,” but it’s actually a type of lipoprotein that carries cholesterol from the liver, where it’s made, to the cells throughout the body. Cholesterol is a vital substance used for various functions, such as hormone production, cell membrane structure, and the synthesis of vitamin D.
  2. Cell Membrane Integrity: Cholesterol transported by LDL is used in the construction and maintenance of cell membranes. It contributes to membrane fluidity and is involved in cell signaling processes.
  3. Precursor for Steroid Hormones and Vitamin D: Cholesterol is a precursor for the synthesis of steroid hormones, including sex hormones like estrogen and testosterone, and adrenal hormones like cortisol. Vitamin D synthesis in the skin also depends on cholesterol.
  4. Insulation and Protection: In the nervous system, cholesterol is essential for the formation of myelin, a fatty substance that insulates neurons and improves the speed of signal transmission.

However, it’s important to maintain balanced levels of LDL in the body. High levels of LDL can lead to the buildup of cholesterol in the arteries, known as atherosclerosis, increasing the risk of heart disease and stroke. This is why LDL is often targeted in efforts to reduce cardiovascular risk.

While LDL has essential functions, like all aspects of metabolism, its balance and regulation are key to maintaining good health.

Ig thats mainly for people who know they have higher levels than they should have.

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:slightly_smiling_face:

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The text you provided is referring to the role of a protein called PCSK9 (proprotein convertase subtilisin/kexin type 9) in the body and the effects of its downregulation.

PCSK9 is a protein that is predominantly produced in the liver 1. It plays a crucial role in regulating the amount of cholesterol in the bloodstream 2. Specifically, PCSK9 binds to the LDL receptor (LDL-R) on the surface of cells, leading to the degradation of the LDL-R] 3. This results in higher plasma LDL-C (low-density lipoprotein cholesterol) levels, also known as “bad” cholesterol 4.

LDL cholesterol is often referred to as “bad” cholesterol because it can build up on the walls of your arteries and form plaque, which can lead to heart disease and stroke 5 10. On the other hand, HDL (high-density lipoprotein), or “good” cholesterol, absorbs cholesterol in the blood and carries it back to the liver, which then flushes it from the body 6. High levels of HDL cholesterol can lower your risk for heart disease and stroke 7.

When PCSK9 is downregulated or removed from your body, it means that less PCSK9 is available to bind to LDL-R. This results in a higher fraction of LDL-R recycling towards the cell surface. As a direct consequence, the cells have the capacity to remove more LDL-C from the circulation, resulting in lower LDL-C plasma levels 8. This is generally considered beneficial because it can reduce the risk of developing atherosclerosis (hardening and narrowing of the arteries) and cardiovascular diseases 9 10.

However, it’s important to note that while lowering LDL levels and increasing HDL levels is generally beneficial, the specific impact on an individual’s health can vary depending on their overall health status and other risk factors. Therefore, any changes to one’s cholesterol levels should be done under the guidance of a healthcare professional.

In summary, the downregulation of PCSK9 leading to a decrease in LDL levels and an increase in the ratio of HDL is generally considered a positive effect in terms of cardiovascular health. However, individual health circumstances can influence this outcome. It’s always best to consult with a healthcare provider for personalized advice.

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Its function seems to be a bit more complex:

PCSK9, or Proprotein Convertase Subtilisin/Kexin Type 9, is an enzyme that plays a significant role in cholesterol metabolism, specifically in the regulation of LDL (low-density lipoprotein) receptors on liver cells. Here’s how PCSK9 functions and its importance:

1. Regulation of LDL Receptors: LDL receptors on the surface of liver cells are crucial for removing LDL cholesterol from the bloodstream. Normally, these receptors bind to LDL particles and facilitate their uptake by liver cells, where the cholesterol is either broken down or reused.
2. Interaction with LDL Receptors: PCSK9 can bind to LDL receptors. When PCSK9 binds to LDL receptors, it leads to their degradation. This means fewer LDL receptors are available on the liver cells to remove LDL cholesterol from the blood.
3. Impact on Blood Cholesterol Levels: Because PCSK9 leads to the degradation of LDL receptors, it indirectly results in higher levels of LDL cholesterol in the bloodstream. This is because the liver has fewer receptors to clear this cholesterol from the blood.
4. Target for Cholesterol-Lowering Therapy: Given its role in maintaining higher levels of LDL cholesterol, PCSK9 has become a target for new cholesterol-lowering drugs. PCSK9 inhibitors are a class of drugs that can significantly lower blood LDL cholesterol levels. By inhibiting the action of PCSK9, these drugs increase the number of LDL receptors available to clear cholesterol from the bloodstream, thus lowering LDL cholesterol levels.

PCSK9 inhibitors have become an important treatment option, especially for individuals who have genetic conditions that result in high cholesterol levels or those who are at high risk of cardiovascular disease and do not adequately respond to statins or other traditional cholesterol-lowering medications.

With this, it’s hard to say if it can be used even for prevention, as for regulating our LDL, there are receptors.

@El_Capitan_Nemo can this be used even as a prevention or when u think higher LDL may be contributing factor to whatever health issue, but also mostly insignificant one?

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Thank You, Dreamweaver. :pray:

Great question.

I would say that it’s very beneficial for most of the people. Listen to Peter Attia for example https://m.youtube.com/watch?v=xJ6X81Gn83Y

There’s no indication that lowering LDL with PCSK9 inhibition is of any significant side effects in regular population and a lot of indicators that lowering LDL through them is very safe and generally lower LDL is better for cardiovascular health.

Take note it’s not inhibition of production of LDL, but improved clearance, that’s what you want to remove the “bad” particles, but leave production needed for your body intact.

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ok, as long as your body hasn’t grown “used to” PCSK9 function :slight_smile:

Meaning that maybe if a relatively healthy person looped this audio, there could be some risks associated.

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It’s a bit more nuanced than that. While it’s true that PCSK9 acts as a regulator that increases LDL cholesterol levels by promoting the degradation of LDL receptors, and its inhibition can lead to lower LDL levels, which is beneficial in reducing cardiovascular risk, the complete role of PCSK9 in human physiology is not fully understood. Here’s a more detailed perspective:

1. PCSK9 and LDL Regulation: In the context of LDL cholesterol regulation, PCSK9 does act as a kind of obstacle by reducing the number of LDL receptors available to clear LDL from the bloodstream. Inhibiting PCSK9 increases the availability of LDL receptors, thereby lowering LDL cholesterol levels. This is clearly beneficial for individuals with conditions like familial hypercholesterolemia or those at high risk for heart disease.
2. Possible Other Roles of PCSK9: The full range of PCSK9’s functions in human biology isn’t completely understood. While its primary known role is in lipid metabolism, particularly in managing LDL cholesterol levels, it’s possible that PCSK9 could have other roles that are not yet fully elucidated. Many proteins and enzymes in the body have multiple functions, some of which may not be apparent until they are absent or inhibited.
3. Long-term Effects of PCSK9 Inhibition: Since PCSK9 inhibitors are a relatively recent development in medicine, the long-term effects of significant PCSK9 inhibition are still being studied. While these medications have been shown to be effective and generally safe in lowering LDL cholesterol, the full long-term implications of drastically lowering PCSK9 activity are still being researched.
4. Balance in Physiological Regulation: In biology, most regulatory mechanisms have evolved to maintain balance or homeostasis. While PCSK9’s role in increasing LDL levels might seem purely negative, especially from the perspective of cardiovascular risk, it’s part of a complex system of lipid regulation. The body’s regulatory systems often have checks and balances that aren’t fully appreciated until one element is altered or removed.

In summary, while inhibiting PCSK9 is currently seen as a beneficial strategy for lowering LDL cholesterol and thus reducing cardiovascular risk, it would be an oversimplification to label PCSK9 as merely an obstacle with no necessary role. Its complete physiological role and the full implications of its inhibition are subjects of ongoing research. In medicine and biology, it’s important to consider the complexity and interconnectedness of different systems before concluding that the removal or complete inhibition of one element is unequivocally beneficial.

I only meant to say, given what’s currently available to quickly find and read, there seem to be lots of unknowns, therefore wanted to confirm with Dream before more intensive use.

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What a title lmao

Also, this should be beneficial now since it’s holiday and maybe some ate a lot of food with trans fat (couldn’t be me jk) that raises LDL.

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Minimal to no risks still. Yes, I doubt this field is for looping, but otherwise it’s generally agreed that lowering LDL through clearance promotion, not synthesis inhibition, is a very safe strategy.

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very very important audio.

use and enjoy.

life changer.

thank you for your work,Dream!

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Ok, if ur relatively healthy, loop it for entire day and we will check u up with tarots :wink:

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I don’t recommend looping, but PCSK9 mechanism was discovered through people who didn’t have it at all and have lower LDL without any negative health consequences. PCSK9, a Review of the Progress from Discovery to Therapy – Fight Aging!

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Ok, will check it up. Thanks

My note is, I’m not advising against, just generally calling up for caution mainly in regards to ppl who haven’t confirmed or significant issues related to LDL, since from description we didn’t rly get information and guidance that may be needed for at least assuring some ppl.

So far I have played it 3 times and while, mostly unknown sensations, I think I feel a little bit of clearance. (I only have confirmed some discrepancy (18/8) in blood pressure of each hand, nothing further yet or maybe anymore)

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Yes, it’s a debatable topic, but mainly through overuse of statins, that are great medicine, but can’t just be pushed in large doses without consideration. PCSK9 is established and very promising pathway. (I listened to Peter Attia a lot and agree with many of his views :slightly_smiling_face:)

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This is great! Thank you so much :pray:t4:

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This audio x 3
Alchemical Jing Charged Blood x 3
Negative Ion Charged Plasma x 3

And wow. I feel like i had a full blood transfusion with the most exquisite fresh brand new one put in the old one’s place.

Thank you Captain for this :pray:

I think im gonna make a post about blood, lymph and circulation, ive have tried so many different mini stacks and each one feels different and deliver different benefits depending what they are combined with. its so cool!

But im updating all the old big Posts ive done in the past with all new fields that can apply to them, so it might take a while to make this one, but honestly try this mini one i did today and see how you like it!

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I would definitely read it.

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