By that I meant, avoiding that PBYO detoxes your brain and removes harmful concentration of certain chemicals, which might reduce your boost not remove the wiring done or being done 
Having super high concentration of Superhuman genius’s chemicals isn’t natural.
But PBOY or autism, none of them removes the new growth it merely trims the detrimental overgrowth (it’s something that your brain does naturally when you are young and your brain is developing).