Eye color is created because of the amount of melanin (eumelanin/pheomelanin) in a particular layer in the iris. I was thinking of either:
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Turning eumelanin to pheomelanin. Eumelanin makes eyes brown or blue depending on the amount, and pheomelanin makes eyes green, which is really a yellow layer on top of the blue.
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Create less eumelanin using the OCA2 gene. It is possible, there are some people who have had complete eye color changes on detoxes and such. And there are of course people, who have eye color changes throughout their life for unknown reasons.
