Topical treatment for benign Acanthosis nigricans, the types which are not caused by (or remain even after treatment of primary cause, such as) insulin resistance, obesity, cancers, syndromes, medication, but could be hereditary. Underlying causes and conditions should of course be addressed with lifestyle and health changes, or prescribed medication (e.g. Metformin, weightloss, balanced diet), but instances still exist in otherwise healthy individuals, especially of African-American, Hispanic, and Native American descent.
Current treatment options for acanthosis nigricans
The treatment would ideally address the hyperpigmentation and hyperkeratosis in the common areas affected, which are the skinfold regions such as groin, armpits, neck. From the above article: “While the goal of therapy for AN is to treat the primary cause, cosmetic resolution of AN lesions can be important for patients and their quality of life.”