Fighting the culprit: Streptococcus mutans
Tooth decay often results from the action of Streptococcus mutans (S. mutans), a bacterium that thrives in the moist and sugary environment of the mouth. It forms a biofilm on the teeth, leading to plaque buildup, enamel erosion, and ultimately tooth decay. The researchers found that DIM destroyed 90 percent of the biofilm, preventing bacterial proliferation.
Lead author Ariel Kushmaro, professor in the Avram and Stella Goldstein-Goren Department of Biotechnology Engineering, said DIM has low toxicity and can be added to toothpaste and mouthwash formulations. This integration could significantly enhance dental hygiene and plaque prevention, potentially transforming oral care practices.