What is kisspeptin? Kisspeptin is a protein present in the hypothalamus (a part of the brain that controls the release of several important hormones in the body). Kisspeptin plays a major role in the control of reproductive hormones in both men and women. Specifically, kisspeptin regulates the release of ‘gonadotrophin releasing hormone’ (GnRH) from the hypothalamus. GnRH, in turn, stimulates the release of the hormones, luteinising hormone (LH) and follicle stimulating hormone (FSH) from the p…