https://www.patreon.com/posts/negentropic-88949150
Designed to pulse with the beat.
A.I designed music with a pulsed beat below, made to create within the mindscape a sense of being pulsed with a negentropic ideological concept.
Of the activation of NANOG and LIN28
Oct4, Sox2, Klf4
Some of the Yamanaka factors along a with pulsed telomerase production.
A smart negentropic pulsed rejuvenation chamber.
Made to create within the mindscape a sense of being pulsed with a negentropic ideological concept. Of the activation of NANOG and LIN28Oct4, Sox2, Klf4Some of the Yamanaka factors along a with pulsed telomerase production.
A smart negentropic pulsed rejuvenation chamber for premium subscribers. Partial reprogramming by expression of reprogramming factors (Oct4, Sox2, Klf4 and c-Myc) for short periods of time restores a youthful epigenetic signature to aging cells and extends the life span of a premature aging mouse model. However, the effects of longer-term partial reprogramming in physiologically aging wild-type mice are unknown. Here, we performed various long-term partial reprogramming regimens, including different onset timings, during physiological aging. Long-term partial reprogramming lead to rejuvenating effects in different tissues, such as the kidney and skin, and at the organismal level; duration of the treatment determined the extent of the beneficial effects. The rejuvenating effects were associated with a reversion of the epigenetic clock and metabolic and transcriptomic changes, including reduced expression of genes involved in the inflammation, senescence and stress response pathways.
Overall, our observations indicate that partial reprogramming protocols can be designed to be safe and effective in preventing age-related physiological changes. We further conclude that longer-term partial reprogramming regimens are more effective in delaying aging phenotypes than short-term reprogramming.” Telomerase, also called terminal transferase, is a ribonucleoprotein that adds a species-dependent telomere repeat sequence to the 3’ end of telomeres. A telomere is a region of repetitive sequences at each end of the chromosomes of most eukaryotes. Telomeres protect the end of the chromosome from DNA damage or from fusion with neighbouring chromosomes Nanog; These cells offer an important area of study because of their ability to maintain pluripotency. In other words, these cells have the ability to become virtually any cell of any of the three germ layers (endoderm 1, ectoderm, mesoderm). Lin28; Mice genetically altered to produce LIN28 during their lifespan showed improved hair growth19 and healthy tissue regeneration on added puncture wounds19 in later life stages.19 While the mice could regenerate limbs, they could not repair damaged heart tissue. Appropriate drugs replicated the regeneration in unaltered mice, using the same metabolic paths. The drugs increased the subjects’ metabolic rates, evidently causing the body to heal at higher rates. The effects of Lin28a activation faded with age.1920
Use once or twice every 3-4 days, this is not to spam for long periods of time, rather to augment health and healing. "
